PXD007281 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Liver proteomics of the HMDP - Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease |
Description | Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease. Unfortunately, our understanding of the contributing pathways that initiate and advance hepatosteatosis to subsequent complications is still poorly understood. Here, we take advantage of recent developments in “omics” technologies to perform high resolution proteomics (>5000 proteins) and quantitative lipidomics (>300 lipids) on livers from 107 genetically diverse inbred mouse strains from the hybrid mouse diversity panel. Integration of these data allowed us to define novel regulators of lipid metabolism in the liver. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:14:26.185.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Benjamin Parker |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-08-16 02:11:27 | ID requested | |
1 | 2021-03-04 12:56:56 | announced | |
⏵ 2 | 2024-10-22 04:14:26 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
curator keyword: Biological |
submitter keyword: HMDP, hybrid mouse diversity panel, liver, proteome wide association study,genetic reference panel |
Contact List
Benjamin Parker |
contact affiliation | The University of Sydney |
contact email | benjamin.parker@sydney.edu.au |
lab head | |
Benjamin Parker |
contact affiliation | The University of Melbourne |
contact email | ben.parker@unimelb.edu.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD007281
- Label: PRIDE project
- Name: Liver proteomics of the HMDP - Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease