PXD007267
PXD007267 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Probing endogenous peptide acceptor substrate specificities of TbSTT3A and TbSTT3B |
| Description | We performed glycoproteomics on endogenous parasite glycoproteins using sequential endoglycosidase-H and peptide-N-glycosidase-F digestions, the latter in the presence of H2[18O]. This allowed us to assess the relative occupancies of native N-glycosylation sites by endoglycosidase-H resistant N-glycans originating from Man5GlcNAc2-PP-dolichol transferred by TbSTT3A, and endoglycosidase-H sensitive N-glycans originating from Man9GlcNAc2-PP-dolichol transferred by TbSTT3B. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_04:14:02.474.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD007267 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Michele Tinti |
| SpeciesList | scientific name: Trypanosoma brucei; NCBI TaxID: 5691; |
| ModificationList | Oxidation; Carbamidomethyl |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2017-08-14 06:20:37 | ID requested | |
| 1 | 2017-09-20 01:18:25 | announced | |
| 2 | 2017-09-21 06:46:37 | announced | Updated publication reference for PubMed record(s): 28928222. |
| ⏵ 3 | 2024-10-22 04:14:03 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Jinnelov A, Ali L, Tinti M, G, ΓΌ, ther MLS, Ferguson MAJ, display different and predictable peptide acceptor specificities. J Biol Chem, 292(49):20328-20341(2017) [pubmed] |
| 10.6019/PXD007267; |
| 10.1074/jbc.m117.810945; |
Keyword List
| curator keyword: Biological |
| submitter keyword: Trypanosoma, glycoproteomics, oligosaccharyltransferase, N-linked glycosylation, STT3, glycoprotein biosynthesis, parasitology |
Contact List
| Michael Ferguson | |
|---|---|
| contact affiliation | The Wellcome Centre for Anti-Infectives Research Ferguson lab School of Life Sciences University of Dundee Dow Street, Dundee DD1 5EH, Scotland, UK |
| contact email | m.a.j.ferguson@dundee.ac.uk |
| lab head | |
| Michele Tinti | |
| contact affiliation | Dundee University |
| contact email | m.tinti@dundee.ac.uk |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD007267 |
| PRIDE project URI |
Repository Record List
[ + ]
to receive all new ProteomeXchange dataset release announcements!
