PXD007258

PXD007258 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human hepatic stellate cell-derived extracellular vesicles LC-MSMS
Description	Activation and migration of hepatic stellate cells (HSCs) followed by matrix deposition are characteristics of liver fibrosis. Several studies have shown the importance of hepatocyte and endothelial cell-derived extracellular vesicles (EVs) in liver pathobiology. However, less is known about the role of HSC-derived EVs in liver diseases. In this study, we investigated the molecules released through HSC-derived EVs and whether these can promote fibrosis.
HostingRepository	PRIDE
AnnounceDate	2018-10-18
AnnouncementXML	Submission_2018-10-18_11:26:27.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD007258
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Enis Kostallari
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Ammonia-loss; Dehydrated; Oxidation; Acetyl; Carbamidomethyl
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-08-12 05:47:58	ID requested
⏵ 1	2018-10-18 11:26:29	announced

Publication List

Kostallari E, Hirsova P, Prasnicka A, Verma VK, Yaqoob U, Wongjarupong N, Roberts LR, Shah VH, Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2. Hepatology, 68(1):333-348(2018) [pubmed]

Kostallari E, Hirsova P, Prasnicka A, Verma VK, Yaqoob U, Wongjarupong N, Roberts LR, Shah VH, Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2. Hepatology, 68(1):333-348(2018) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: hepatic stellate cells, liver, extracellular vesicles, LC-MSMS

curator keyword: Biological

submitter keyword: hepatic stellate cells, liver, extracellular vesicles, LC-MSMS

Contact List

Vijay H. Shah, M.D.
contact affiliation	Division Chair of GI/Hepatology Mayo Clinic Rochester, MN USA 55905
contact email	Shah.Vijay@mayo.edu
lab head
Enis Kostallari
contact affiliation	Mayo Clinic
contact email	enis.kostallari@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD007258
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD007258

PRIDE project URI

Repository Record List

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