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PXD007217

PXD007217 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePlasma proteomic profiling of small size HER2-positive breast cancer
DescriptionLymph node status is a crucial predictor for the overall survival of invasive breast cancer. However, lymph node involvement is only detected in about half of HER2 positive patients. Currently, there are no biomarkers available for distinguishing small size HER2-positive breast cancers with different lymph node statuses. Thus, in the present study, we applied label-free quantitative proteomic strategy to construct plasma proteomic profiles of ten patients with small size HER2-positive breast cancers (5 patients with lymph node metastasis versus 5 patients with lymph node metastasis).
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:13:50.944.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTao Zhou
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-08-08 07:56:55ID requested
12018-02-08 02:02:28announced
22024-10-22 04:13:53announced2024-10-22: Updated project metadata.
Publication List
Chen L, Zhao W, He J, Li L, Meng D, Cai D, Yu J, Chen D, Wu Y, Zhou T, Label-Free Quantitative Proteomic Screening of Candidate Plasma Biomarkers for the Prognosis of Breast Cancer with Different Lymph Node Statuses. Proteomics Clin Appl, 12(3):e1700117(2018) [pubmed]
10.1002/prca.201700117;
Keyword List
curator keyword: Biomedical
submitter keyword: shotgun proteomics,breast cancer, lymph node, label-free, plasma biomarker, prognosis
Contact List
Tao Zhou
contact affiliationCentral Laboratory, Wuxi Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University
contact emailzhoutao@njmu.edu.cn
lab head
Tao Zhou
contact affiliationCentral Laboratory, Wuxi Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University
contact emailzhoutao@njmu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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