PXD007168

PXD007168 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of [PSI+] yeast strain
Description	The yeast Sup35 protein is a subunit of the translation termination factor, and its conversion to the [PSI+] prion state leads to more translational read-through. Although extensive studies have been done on [PSI+], changes at the proteomic level have not been performed exhaustively. We therefore used a SILAC-based quantitative mass spectrometry approach and identified 4187 proteins from both [psi-] and [PSI+] strains. Surprisingly, there was very little difference between the two proteomes under standard growth conditions.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:39:57.155.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Patrick Hau Wing Chan
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	carbamoylated residue; monohydroxylated residue
Instrument	Bruker Daltonics instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2017-08-02 02:45:49	ID requested
1	2018-10-23 16:30:46	announced
⏵ 2	2024-10-22 04:40:05	announced	2024-10-22: Updated project metadata.

Chan PHW, Lee L, Kim E, Hui T, Stoynov N, Nassar R, Moksa M, Cameron DM, Hirst M, Gsponer J, Mayor T, ] cells can promote aneuploidy. Sci Rep, 7(1):8442(2017) [pubmed]

10.1038/s41598-017-07999-8;

curator keyword: Biological

submitter keyword: Yeast prion, proteomics, Sup35, mass spectrometry, SILAC, aneuploidy, amyloids

Thibault Mayor
contact affiliation	Associate Professor
contact email	mayor@msl.ubc.ca
lab head
Patrick Hau Wing Chan
contact affiliation	University of British Columbia
contact email	hauwing2004@hotmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD007168

PRIDE project URI

• PRIDE
  1. PXD007168
     1. Label: PRIDE project
     2. Name: Proteomic analysis of [PSI+] yeast strain