PXD006929

PXD006929 is an original dataset announced via ProteomeXchange.

Title	He Xiang - BfrB - Systematic Identification of Mycobacterium tuberculosis Effectors Reveals that BfrB Suppresses Innate Immunity
Description	To identify the macrophage binding partner of Mtb BfrB, we selected and purified BfrB tagged with GST, and incubated it with THP-1 lysates before performing GST Pullodwn. Then the eluted protein were examined by sliver stain. Using mass spectrometry, we identified a protein with an apparent molecular mass of 28 KDa as RPS3, an essential subunit of NF-κB involved in the regulation of key genes in rapid cellular activation response.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:39:10.026.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD006929
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	He Xiang
SpeciesList	scientific name: Mycobacterium tuberculosis; NCBI TaxID: NCBITaxon:1773; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	ultraflex

Revision	Datetime	Status	ChangeLog Entry
0	2017-07-11 02:47:58	ID requested
1	2017-10-17 02:59:43	announced
⏵ 2	2024-10-22 04:39:14	announced	2024-10-22: Updated project metadata.

10.1074/mcp.ra117.000296;

10.6019/PXD006929;

He X, Jiang HW, Chen H, Zhang HN, Liu Y, Xu ZW, Wu FL, Guo SJ, Hou JL, Yang MK, Yan W, Deng JY, Bi LJ, Zhang XE, Tao SC, Effectors Reveals that BfrB Suppresses Innate Immunity. Mol Cell Proteomics, 16(12):2243-2253(2017) [pubmed]

curator keyword: Biological

submitter keyword: BfrB RPS3

Tao Shengce
contact affiliation	Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, China
contact email	taosc@sjtu.edu.cn
lab head
He Xiang
contact affiliation	Shanghai Jiao Tong University
contact email	hexiangsky@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/10/PXD006929

PRIDE project URI

• PRIDE
  1. PXD006929
     1. Label: PRIDE project
     2. Name: He Xiang - BfrB - Systematic Identification of Mycobacterium tuberculosis Effectors Reveals that BfrB Suppresses Innate Immunity