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PXD006895 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSubCellBarcode: Scalable proteome-wide mapping of protein localization and relocalization
DescriptionWe have devised a simple and robust LC-MS/MS compatible protocol for subcellular protein localization studies. Here, we combine it with in depth proteome profiling and utilize the resulting dataset to predict the subcellular localization of more than 12000 proteins in 5 human cancer cell lines. The data allows for exploration of both cell line specific and perturbation related protein localization changes as well as domain and splice variant effects and protein complex formation. The data is made accessible through the online resource www.subcellbarcode.org.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMattias Vesterlund
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-07-07 03:44:38ID requested
12019-01-03 12:54:51announced
22019-01-07 02:14:44announcedUpdated publication reference for PubMed record(s): 30609389.
Publication List
Orre LM, Vesterlund M, Pan Y, Arslan T, Zhu Y, Fernandez Woodbridge A, Frings O, Fredlund E, Lehti, ö J, SubCellBarCode: Proteome-wide Mapping of Protein Localization and Relocalization. Mol Cell, 73(1):166-182.e7(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Subcellular, Subcellular protein localization, Human, Cancer, MCF7, U251, A431, HCC827, NCI-H322, HiRIEF, LC-MS.
Contact List
Janne Lehtiö
contact affiliationDept. Oncology Pathology, Karolinska Institutet, and Scilifelab, Stockholm, Sweden
contact emailjanne.lehtio@ki.se
lab head
Mattias Vesterlund
contact affiliationKarolinska Institutet
contact emailmattias.vesterlund@ki.se
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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