PXD006750

PXD006750 is an original dataset announced via ProteomeXchange.

Title	T cells facilitate brain metastasis of breast cancer.
Description	Three breast cancer cell lines were co-cultured with T cells isolated from normal donors, in 3: 1 ratio. As controls, the breast cancer cells were cultured without T cells for three days. All cell cultures were washed three times with PBS to remove T cells before they were scraped and collected in 1.5 mL Eppendorf tubes. Three additional washing steps with PBS were applied. After removing the supernatant, the cell pellets were immediately snap-frozen on dry-ice and stored in -80 °C until the time of preparation. After thawing the samples, they were prepared and measured on nano LC.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:38:40.939.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dana Mustafa
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2017-06-19 08:08:09	ID requested
1	2018-01-25 01:31:05	announced
⏵ 2	2024-10-22 04:38:45	announced	2024-10-22: Updated project metadata.

10.1007/s00401-018-1806-2;

Mustafa DAM, Pedrosa RMSM, Smid M, van der Weiden M, de Weerd V, Nigg AL, Berrevoets C, Zeneyedpour L, Priego N, Valiente M, Luider TM, Debets R, Martens JWM, Foekens JA, Sieuwerts AM, Kros JM, T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression. Acta Neuropathol, 135(4):581-599(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: breast cancer, T cell response, human.,brain metastasis

Johan M. Kros
contact affiliation	Department of Pathology, Erasmus MC
contact email	j.m.kros@erasmusmc.nl
lab head
Dana Mustafa
contact affiliation	Erasmus MC
contact email	d.mustafa@erasmusmc.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD006750

PRIDE project URI

• PRIDE
  1. PXD006750
     1. Label: PRIDE project
     2. Name: T cells facilitate brain metastasis of breast cancer.