PXD006691

PXD006691 is an original dataset announced via ProteomeXchange.

Title	Stability of peptide fragmentation patterns
Description	Our study aims to determine the stability of fragmetnation patterns of peptides upon collision-induced dissociation (CID). Recent studies reported that for a minority of peptides, CID fragmentation leads to non-reproducible fragmentation spectra and therefore impaired identification. In order to study the fragmentation behavior, we first identified peptides that exhibit different fragmentation patterns. In order to reveal the cause, we selected a subset of the peptides and studied the dependency of abundance of distinct fragmentation patterns with collision energy settings and with of the isolation window.
HostingRepository	PRIDE
AnnounceDate	2019-02-25
AnnouncementXML	Submission_2019-02-25_02:10:58.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andreas Schmidt
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600+

Revision	Datetime	Status	ChangeLog Entry
0	2017-06-09 07:55:23	ID requested
⏵ 1	2019-02-25 02:10:59	announced

Ammar C, Berchtold E, Csaba G, Schmidt A, Imhof A, Zimmer R, Multi-Reference Spectral Library Yields Almost Complete Coverage of Heterogeneous LC-MS/MS Data Sets. J Proteome Res, 18(4):1553-1566(2019) [pubmed]

submitter keyword: peptide fragmentation, collision-induced dissociation, tandem MS, peptide identification

Axel Imhof
contact affiliation	Protein Analysis Unit (ZfP) BioMedical Center, LMU Munich Grosshaderner Strasse 9 82152 Planegg-Martinsried Tel. +49 89 2180 75420
contact email	imhof@lmu.de
lab head
Andreas Schmidt
contact affiliation	Adolf-Butenandt-Institut
contact email	A.Schmidt@med.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/02/PXD006691

PRIDE project URI

• PRIDE
  1. PXD006691
     1. Label: PRIDE project
     2. Name: Stability of peptide fragmentation patterns