PXD006662 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic characterization of transcription and splicing factors associated with a more invasive phenotype in colorectal cancer |
Description | To find new transcription and splicing factors associated with the metastatic phenotype we used a concatenated tandem array of consensus transcription factors response elements (catTFRE) on nuclear extracts of colon cancer cell lines. We used two different isogenic pairs of colorectal metastatic cells, KM12SM/KM12C and SW620/480. Proteins were pulled-down using biotinylated DNA sequences and streptavidin beads and analyzed by LC-MSMS. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:16:13.824.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Consuelo Marín-Vicente |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-06-06 07:14:56 | ID requested | |
1 | 2017-11-15 01:35:38 | announced | |
⏵ 2 | 2024-10-22 04:16:14 | announced | 2024-10-22: Updated project metadata. |
Publication List
Torres S, Garc, í, a-Palmero I, Mar, í, n-Vicente C, Bartolom, é RA, Calvi, ñ, o E, Fern, á, ndez-Ace, ñ, ero MJ, Casal JI, Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer. J Proteome Res, 17(1):252-264(2018) [pubmed] |
10.1021/acs.jproteome.7b00548; |
Keyword List
curator keyword: Biomedical |
submitter keyword: Human, LC-MSMS, transcription, colon cancer, splicing, cell lines, metastasis |
Contact List
J. Ignacio Casal Alvarez |
contact affiliation | Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain |
contact email | icasal@cib.csic.es |
lab head | |
Consuelo Marín-Vicente |
contact affiliation | CIB-CSIC |
contact email | cmarin@cib.csic.es |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/11/PXD006662 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD006662
- Label: PRIDE project
- Name: Proteomic characterization of transcription and splicing factors associated with a more invasive phenotype in colorectal cancer