<<< Full experiment listing

PXD006641

PXD006641 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomic analysis of oocytes from high-fat diet (HFD)-fed and normal diet mice
DescriptionIn order to establish an obese mouse model, female mice were continuously fed with a high-fat diet (HFD) or a normal diet (control) for 16 weeks beginning at three weeks of age. In this paper, these mice are termed ‘HFD mice’ and ‘control mice’, respectively. Accordingly, we call their oocytes ‘HFD oocytes’ and ‘control oocytes’. Substantial evidence indicates that the effects of maternal obesity on embryo/offspring development can be attributed to factors within the oocyte (9). To identify such potential effectors, we performed a comparative proteomic analysis of ovulated MII oocytes from control and HFD mice.
HostingRepositoryPRIDE
AnnounceDate2018-05-24
AnnouncementXMLSubmission_2018-05-24_09:05:37.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterhao zhang
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; acetylated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-06-01 01:14:13ID requested
12018-05-24 09:05:38announced
Publication List
Wang H, Cheng Q, Li X, Hu F, Han L, Zhang H, Li L, Ge J, Ying X, Guo X, Wang Q, Loss of TIGAR Induces Oxidative Stress and Meiotic Defects in Oocytes from Obese Mice. Mol Cell Proteomics, 17(7):1354-1364(2018) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: quantitative,oocytes,high-fat diet,HFD
Contact List
Guo, Xuejiang
contact affiliationNanjing Med Univ, State Key Lab Reprod Med, Dept Histol & Embryol, 140 Hanzhong Rd, Nanjing 210029, Jiangsu, Peoples R China.
contact emailguo_xuejiang@njmu.edu.cn
lab head
hao zhang
contact affiliationNanjing medical university
contact email542370159@qq.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD006641
PRIDE project URI
Repository Record List
[ + ]