PXD006557

PXD006557 is an original dataset announced via ProteomeXchange.

Title	TAILS N-terminomics of the human dental pulp stroma and the odontoblast layer
Description	We report the targeted analysis of the human dental pulp stroma and the odontoblast layer using the positional proteomics technique TAILS N-terminomics, which allowed us to capture both naturally blocked and unblocked protein N-termini, and to identify differences between e.g. the dental pulp proteomes of older and younger donors. Noteworthy, these differences were most pronounced in the odontoblast region. Note: This study is a follow-up on PXD002264.
HostingRepository	PRIDE
AnnounceDate	2017-10-20
AnnouncementXML	Submission_2017-10-20_02:25:41.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ulrich ECKHARD
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	(R)-5-oxo-1: 4-tetrahydrothiazine-3-carboxylic acid; 2-pyrrolidone-5-carboxylic acid (Glu); alpha-amino acetylated residue; 2x(13)C: 4x(2)H labeled dimethylated residue; 2-pyrrolidone-5-carboxylic acid (Gln); iodoacetamide derivatized residue
Instrument	6520 Quadrupole Time-of-Flight LC/MS

Revision	Datetime	Status	ChangeLog Entry
0	2017-05-22 05:34:18	ID requested
⏵ 1	2017-10-20 02:25:42	announced

Abbey SR, Eckhard U, Solis N, Marino G, Matthew I, Overall CM, The Human Odontoblast Cell Layer and Dental Pulp Proteomes and N-Terminomes. J Dent Res, 97(3):338-346(2018) [pubmed]

ProteomeXchange project tag: Chromosome-centric Human Proteome Project (C-HPP), Human Proteome Project

submitter keyword: LC-MSMS, human, pulp, stroma, odontoblast, CHPP, TAILS, N-terminomics, positional proteomics

Prof. Christopher Mark Overall
contact affiliation	Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada
contact email	chris.overall@ubc.ca
lab head
Ulrich ECKHARD
contact affiliation	University of British Columbia
contact email	ulrich.eckhard@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/10/PXD006557

PRIDE project URI

• PRIDE
  1. PXD006557
     1. Label: PRIDE project
     2. Name: TAILS N-terminomics of the human dental pulp stroma and the odontoblast layer