PXD006473

PXD006473 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	M. bovis BCG PknG physiological substrates
Description	Mycobacterial Ser/Thr kinases play a critical role in bacterial physiology and pathogenesis. Linking kinases to the substrates they phosphorylate in vivo, thereby elucidating their exact functions, is still a challenge. The aim of this work was to associate protein phosphorylation in mycobacteria with important subsequent macro cellular events by identifying the physiological substrates of PknG in Mycobacterium bovis BCG. The study compared the phosphoproteome dynamics during the batch growth of M. bovis BGC versus the respective PknG knock-out mutant (ΔPknG-BCG) strains.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:37:13.949.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kehilwe Nakedi
SpeciesList	scientific name: Mycobacterium bovis BCG str. Pasteur 1173P2; NCBI TaxID: 410289;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-05-09 23:40:13	ID requested
1	2018-03-23 02:12:45	announced
⏵ 2	2024-10-22 04:37:16	announced	2024-10-22: Updated project metadata.

Publication List

10.1074/mcp.ra118.000705;
Nakedi KC, Calder B, Banerjee M, Giddey A, Nel AJM, Garnett S, Blackburn JM, Soares NC, BCG Protein Kinase G (PknG) by Label-free Quantitative Phosphoproteomics. Mol Cell Proteomics, 17(7):1365-1377(2018) [pubmed]

10.1074/mcp.ra118.000705;

Nakedi KC, Calder B, Banerjee M, Giddey A, Nel AJM, Garnett S, Blackburn JM, Soares NC, BCG Protein Kinase G (PknG) by Label-free Quantitative Phosphoproteomics. Mol Cell Proteomics, 17(7):1365-1377(2018) [pubmed]

Keyword List

submitter keyword: Kinases,PknG
Phosphoproteomics
Mycobacteria

submitter keyword: Kinases,PknG

Phosphoproteomics

Mycobacteria

Contact List

Jonathan M Blackburn
contact affiliation	Department of Intergrated Biomedical Sciences Institute of Infectious Disease and molecular medicine
contact email	jonathan.blackburn@uct.ac.za
lab head
Kehilwe Nakedi
contact affiliation	University of Cape Town
contact email	kcnakedi@yahoo.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD006473
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/03/PXD006473

PRIDE project URI

Repository Record List

[ + ]