Updated publication reference for PubMed record(s): 30917324. Intracellular lipids are stored in dedicated organelles called lipid droplets (LDs). While the primary purpose of the storage lipids is fueling the energy demands of cells and organisms, LDs additionally participate in multifmultivarious cellular functions such as the production of lipid hormones, or the role as protein storage depots. The proteins associated with LDs are key to the diverse LD functions. Lipid deposits not only reflect the nutritional status of an organism, but they also affect many organismic parameters such as vitality, food intake, or signaling pathway activities. Currently, we only incompletely understand the mechanism(s) of this cross talk. Here, we functionally characterize the evolutionary conserved LD-associated protein CG9186.