PXD006457

PXD006457 is an original dataset announced via ProteomeXchange.

Title	Lipid droplet-associated Drosophila protein CG9186 interacting proteins
Description	Intracellular lipids are stored in dedicated organelles called lipid droplets (LDs). While the primary purpose of the storage lipids is fueling the energy demands of cells and organisms, LDs additionally participate in multifmultivarious cellular functions such as the production of lipid hormones, or the role as protein storage depots. The proteins associated with LDs are key to the diverse LD functions. Lipid deposits not only reflect the nutritional status of an organism, but they also affect many organismic parameters such as vitality, food intake, or signaling pathway activities. Currently, we only incompletely understand the mechanism(s) of this cross talk. Here, we functionally characterize the evolutionary conserved LD-associated protein CG9186.
HostingRepository	PRIDE
AnnounceDate	2019-02-19
AnnouncementXML	Submission_2019-04-10_05:41:43.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Gereon Poschmann
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	ubiquitination signature dipeptidyl lysine; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2017-05-05 06:36:43	ID requested
1	2019-02-19 09:07:57	announced
⏵ 2	2019-04-10 05:41:45	announced	Updated publication reference for PubMed record(s): 30917324.

Werthebach M, Stewart FA, Gahlen A, Mettler-Altmann T, Akhtar I, Maas-Enriquez K, Droste A, Eichmann TO, Poschmann G, St, ü, hler K, Beller M, Control of Drosophila Growth and Survival by the Lipid Droplet-Associated Protein CG9186/Sturkopf. Cell Rep, 26(13):3726-3740.e7(2019) [pubmed]

curator keyword: Biological

submitter keyword: drosophila, lipid droplet, shotgun mass spectrometry, CGC9186, protein interaction, affinity purification

Gereon Poschmann
contact affiliation	Molecular Proteomics Laboratory (MPL) Biologisch-Medizinisches Forschungszentrum (BMFZ) Heinrich-Heine-Universität Düsseldorf
contact email	gereon.poschmann@hhu.de
lab head
Gereon Poschmann
contact affiliation	Molecular Proteomics Laboratory
contact email	gereon.poschmann@hhu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/02/PXD006457

PRIDE project URI

• PRIDE
  1. PXD006457
     1. Label: PRIDE project
     2. Name: Lipid droplet-associated Drosophila protein CG9186 interacting proteins