PXD006370

PXD006370 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Lambert_SAINT2096_rBRD4_domain_pulldown_P82_VS5
Description	This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. More precisely, files used in the SAINT express task 2096 are in this dataset. The pulldown experiments using recombinant BRD4 domains acquired on a Velos Orbitrap Elite mass spectrometer are found here. See the README file within "Materials and Methods" and the accompanying files for a complete description of MS data generated.
HostingRepository	MassIVE
AnnounceDate	2018-10-15
AnnouncementXML	Submission_2018-10-15_17:07:32.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Gingras Lab
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	deamidated L-asparagine; deamidated L-glutamine; L-methionine sulfoxide
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-04-24 19:46:23	ID requested
⏵ 1	2018-10-15 17:07:33	announced

Publication List

Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras. Interactome rewiring following pharmacological targeting of BET bromodomains. Mol Cell, in press.

Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras. Interactome rewiring following pharmacological targeting of BET bromodomains. Mol Cell, in press.

Keyword List

submitter keyword: protein interaction, affinity purification, bromodomain, acetylation, AP-MS

submitter keyword: protein interaction, affinity purification, bromodomain, acetylation, AP-MS

Contact List

Anne-Claude Gingras
contact affiliation	LTRI
contact email	gingras@lunenfeld.ca
lab head
Gingras Lab
contact affiliation	Samuel Lunenfeld Research Institute
contact email	gingras@mshri.on.ca
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000080986