PXD006359

PXD006359 is an original dataset announced via ProteomeXchange.

Title	Identification of Siglec ligands in human B cell
Description	Siglecs are a family of receptor-type glycan recognition proteins (lectins) involved in self - nonself discrimination by the immune system. Identification of Siglec ligand(s) is necessary to understand how Siglec-ligand interaction translates to biological outcomes, but is challenging because the interaction is weak. To facilitate identification of Siglec ligands, we adopted proximity labeling method based on tyramide radicalization principle.
HostingRepository	PRIDE
AnnounceDate	2017-09-29
AnnouncementXML	Submission_2017-09-29_09:07:22.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yi-Ju Chen
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2017-04-24 02:40:29	ID requested
⏵ 1	2017-09-29 09:07:23	announced

Chang L, Chen YJ, Fan CY, Tang CJ, Chen YH, Low PY, Ventura A, Lin CC, Chen YJ, Angata T, Identification of Siglec Ligands Using a Proximity Labeling Method. J Proteome Res, 16(10):3929-3941(2017) [pubmed]

curator keyword: Biological

submitter keyword: Siglec, sialic acid, proteomics

Takashi Angata
contact affiliation	Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
contact email	angata@gate.sinica.edu.tw
lab head
Yi-Ju Chen
contact affiliation	Academia Sinica
contact email	tp7249@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD006359

PRIDE project URI

• PRIDE
  1. PXD006359
     1. Label: PRIDE project
     2. Name: Identification of Siglec ligands in human B cell