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DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2017-05-19
  • AnnouncementXML: Submission_2017-06-20_05:42:03.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Kim Gurwitz
  • Title: HIV-Tat treatment of human neurons in vitro over time: towards a model for the molecular pathology of HIV-associated neurocognitive disorders (~90% cell culture confluence dataset)
  • Description: We have used LC-MSMS discovery proteomics to identify the quantitative, cell-wide changes that occur when non-transformed, differentiated human neurons are treated with HIV-Tat over time. This may represent a novel cell culture model for initial HIV-associated neurocognitive disorder progression.
  • SpeciesList: scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
  • ModificationList: No PTMs are included in the dataset
  • Instrument: Q Exactive

Dataset History

VersionDatetimeStatusChangeLog Entry
02017-04-18 01:49:29ID requested
12017-05-19 02:12:50announced
22017-06-20 05:42:04announcedUpdated publication reference for PubMed record(s): 28611588.

Publication List

  1. Gurwitz KT, Burman RJ, Murugan BD, Garnett S, Ganief T, Soares NC, Raimondo JV, Blackburn JM, : Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive Disorders. Front Mol Neurosci, 10():163(2017) [pubmed]

Keyword List

  1. curator keyword: Biomedical
  2. submitter keyword: Human neuronal cells, HIV-Tat, HIV associated neurocognitive disorders, LCMSMS

Contact List

    Prof. Jonathan Blackburn
    • contact affiliation: Department of Integrative Biomedical Science, Blackburn Group, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    • contact email: jonathan.blackburn@uct.ac.za
    • lab head:
    Kim Gurwitz
    • contact affiliation: University of Cape Town
    • contact email: kgurwitz@gmail.com
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List
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