PXD006305

PXD006305 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Rat liver treated by PCN
Description	The combination analyses of transcriptomics, proteomics, phosphoproteomics, and metabolomics in rat liver after repeated oral doses of PXR agonist, PCN, for 7 days were conducted to understand the roles for PXR on non-genotoxic signaling and energy homeostasis. mRNA and proteins in homogenate supernatant, membrane, and cytosolic fractions prepared from the liver were analyzed.
HostingRepository	jPOST
AnnounceDate	2018-01-01
AnnouncementXML	Submission_2022-09-18_02:44:46.098.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sumio Ohtsuki
SpeciesList	scientific name: Rattus rattus (Black rat); NCBI TaxID: 10117;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-04-14 21:25:55	ID requested
1	2017-12-31 07:00:06	announced
2	2018-09-19 00:08:29	announced	Updated CV, FTP location and Modification list.
3	2021-02-04 16:58:57	announced	2021-02-04: Updated FTP location.
⏵ 4	2022-09-18 02:44:46	announced	2022-09-18: Updated FTP location.

Publication List

Nagahori H, Nakamura K, Sumida K, Ito S, Ohtsuki S, Combining Genomics To Identify the Pathways of Post-Transcriptional Nongenotoxic Signaling and Energy Homeostasis in Livers of Rats Treated with the Pregnane X Receptor Agonist, Pregnenolone Carbonitrile. J Proteome Res, 16(10):3634-3645(2017) [pubmed]

Nagahori H, Nakamura K, Sumida K, Ito S, Ohtsuki S, Combining Genomics To Identify the Pathways of Post-Transcriptional Nongenotoxic Signaling and Energy Homeostasis in Livers of Rats Treated with the Pregnane X Receptor Agonist, Pregnenolone Carbonitrile. J Proteome Res, 16(10):3634-3645(2017) [pubmed]

Keyword List

submitter keyword: rat, liver, PCN, SWATH, subcellular fractionation

submitter keyword: rat, liver, PCN, SWATH, subcellular fractionation

Contact List

Sumio Ohtsuki
lab head
Sumio Ohtsuki
contact affiliation	Kumamoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000258/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000258/