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PXD006298

PXD006298 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTMT-FASP-LC-MS analysis of human pediatric omental biopsies
DescriptionCardiovascular disease (CVD) is exceedingly severe in patients with chronic kidney disease (CKD) and further aggravated by peritoneal dialysis (PD), exposing the patients to excessive amounts of intraperitoneal glucose. Children are devoid of pre-existing CVD and give insight into specific uremia and PD induced pathomechanisms. Fat surrounded omental arterioles beyond PD fluid penetration level were microdissected from uremic children at time of first PD catheter insertion (n=8), children on PD (n=5), and age and gender matched non-uremic children as controls (n=6). Adjacent sections of 4 arterioles per patient were used for proteomic analyses.
HostingRepositoryPRIDE
AnnounceDate2019-11-08
AnnouncementXMLSubmission_2019-11-08_08:04:43.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKlaus Kratochwill
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-04-13 08:06:42ID requested
12019-11-08 08:04:44announced
Publication List
Bartosova M, Schaefer B, Bermejo JL, Tarantino S, Lasitschka F, Macher-Goeppinger S, Sinn P, Warady BA, Zaloszyc A, Parapatics K, M, รก, jek P, Bennett KL, Oh J, Aufricht C, Schaefer F, Kratochwill K, Schmitt CP, Complement Activation in Peritoneal Dialysis-Induced Arteriolopathy. J Am Soc Nephrol, 29(1):268-282(2018) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Human, Omentum, TMT, FASP, Arterioles, Microdissection, Peritoneal Dialysis, Uremia
Contact List
Klaus Kratochwill
contact affiliationDepartment of Pediatrics and Adolescent Medicine, Medical University of Vienna, Austria
contact emailklaus.kratochwill@meduniwien.ac.at
lab head
Klaus Kratochwill
contact affiliationMedical University of Vienna
contact emailklaus.kratochwill@meduniwien.ac.at
dataset submitter
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Dataset FTP location
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