PXD006297

PXD006297 is an original dataset announced via ProteomeXchange.

Title	Membrane Proteome Profiling of Peripheral Immune Cells in Non-Small Cell Lung Cancer Patients Treated with First Line Combination Chemotherapy
Description	Four lung adenocarcinoma patients with progression free survival (PFS) ranged from 2.13 to 14.5 months were recruited in the study. Paired PBMCs were collected before and after first regimen of PEM/CIS treatment for individualized analysis of membrane proteome profiles. The membrane protein fractions were purified from PBMCs, subjected to gel-assisted digestion, labeled with iTRAQ reagents, fractionated by high-pH reversed phase StageTip, and analyzed in duplicate by LC-MS/MS. Protein identification and quantitation was obtained by using Mascot with 1% false discovery rate and Multi-Q.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:02:49.911.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Denise Utami Putri
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ4plex-116 reporter+balance reagent acylated residue; methylthiolated residue; monohydroxylated residue; deamidated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2017-04-13 08:00:47	ID requested
1	2018-01-02 03:36:21	announced
⏵ 2	2024-10-22 04:02:54	announced	2024-10-22: Updated project metadata.

10.1002/prca.201700040;

Putri DU, Feng PH, Hsu YH, Lee KY, Jiang FW, Kuo LW, Chen YJ, Han CL, Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics. Proteomics Clin Appl, 12(2):(2018) [pubmed]

curator keyword: Biomedical

submitter keyword: immune cell profiling,llung adenocarcinoma, membrane proteomics

Chia-Li Han
contact affiliation	Master Program for Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Taipei 100, Taiwan
contact email	was@tmu.edu.tw
lab head
Denise Utami Putri
contact affiliation	Taipei Medical University, Taipei, Taiwan
contact email	denise.utami@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD006297

PRIDE project URI

• PRIDE
  1. PXD006297
     1. Label: PRIDE project
     2. Name: Membrane Proteome Profiling of Peripheral Immune Cells in Non-Small Cell Lung Cancer Patients Treated with First Line Combination Chemotherapy