<<< Full experiment listing

PXD006236

PXD006236 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAccumulated ion monitoring for improved sensitivity
DescriptionThis work aimed to improve sensitivity of targeted detection by orbitrap mass spectrometers. Co-isolation of contaminant ions was identified as the major factor limiting sensitivity, and LOD of both PRM and accumulated precursor ion scanning (AIM) was improved by increased chromatographic resolution.
HostingRepositoryPRIDE
AnnounceDate2017-08-24
AnnouncementXMLSubmission_2017-08-24_02:19:04.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlex Kentsis
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentOrbitrap Fusion ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-04-03 02:06:30ID requested
12017-08-24 02:19:05announced
Publication List
Cifani P, Kentsis A, High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer. Mol Cell Proteomics, 16(11):2006-2016(2017) [pubmed]
Keyword List
curator keyword: Technical
submitter keyword: targeted-MS, orbitrap, phosphorylation, quantitative-MS, PRM
Contact List
Alex Kentsis
contact affiliationMolecular Pharmacology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
contact emailkentsisresearchgroup@gmail.com
lab head
Alex Kentsis
contact affiliationMemorial Sloan Kettering Cancer Center
contact emailkentsisresearchgroup@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
[ + ]