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PXD006200

PXD006200 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleR2TP_BioID-MS
DescriptionThe R2TP/Prefoldin-like (R2TP/PFDL) complex is a cochaperone complex involved in the assembly of a number of critical protein complexes. Here we use proximity-dependent biotinylation (BioID) coupled to mass spectrometry to confirm interactions of ZNHIT2, a cofactor of R2TP/PFDN, identified by TAP-MS.
HostingRepositoryPRIDE
AnnounceDate2018-10-24
AnnouncementXMLSubmission_2018-10-24_14:32:38.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristian Poitras
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-03-29 01:33:40ID requested
12018-10-24 14:32:40announced
Publication List
Cloutier P, Poitras C, Durand M, Hekmat O, Fiola-Masson É, Bouchard A, Faubert D, Chabot B, Coulombe B, R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein. Nat Commun, 8():15615(2017) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Human, Flp-In T-REx HEK 293, BioID, LC-MSMS, ZNHIT2, U5 snRNP, R2TP/PFDN
Contact List
Benoit Coulombe
contact affiliationInstitut de recherches cliniques de Montréal (IRCM), Translational proteomics
contact emailbenoit.coulombe@ircm.qc.ca
lab head
Christian Poitras
contact affiliationLaboratory of Gene Transcription and Proteomics Discovery Platform, Institut de recherches cliniques de Montréal, 110 avenue des Pins Ouest, Montréal, QC H2W 1R7, Canada
contact emailchristian.poitras@ircm.qc.ca
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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