PXD006167

PXD006167 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analysis of phospho-proteome change following MST3/4 depletion
Description	Mammalian STE20-like protein kinases 3 and 4 (MST3/4) have recently emerged as crucial regulators of several key cellular processes such as proliferation, migration, and polarity. However, the downstream target pathways which are regulated by the kinase activity of MST3/4 remain poorly characterised. To assess downstream targets of MST3/4 kinases in an unbiased manner, we transiently co-depleted MST3 and MST4 in HeLa cells by siRNA and quantified the change in their phospho-proteome using SILAC.
HostingRepository	PRIDE
AnnounceDate	2022-02-28
AnnouncementXML	Submission_2022-02-28_08:30:50.352.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Faraz Mardakheh
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-03-24 05:10:38	ID requested
⏵ 1	2022-02-28 08:30:50	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

curator keyword: Biological
submitter keyword: MST3
MST4
CCM3
GCKIII
FAM65A
STRIPAK

curator keyword: Biological

submitter keyword: MST3

MST4

CCM3

GCKIII

FAM65A

STRIPAK

Contact List

Faraz Mardakheh
contact affiliation	Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, The United Kingdom.
contact email	f.mardakheh@qmul.ac.uk
lab head
Faraz Mardakheh
contact affiliation	Barts Cancer Institute
contact email	f.mardakheh@qmul.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD006167
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD006167

PRIDE project URI

Repository Record List

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