PXD006108

PXD006108 is an original dataset announced via ProteomeXchange.

Title	Predictive biomarkers of sperm quality in sturgeon spermatozoa
Description	In this study, we used the iTRAQ proteomics approach to perform proteomic profiling of spermatozoa associated with sperm quality in sturgeons. The results showed 291 and 359 differentially expressed proteins in A. baerii and A. schrenckii, respectively, of which 72 were common to both species and all were upregulated in high quality compared with low quality samples. The differentially expressed proteins were mainly categorized into the generation of precursor metabolites and energy and oxidation, and they were localized to the mitochondria. Three distinguishing pathways, Arginine and proline metabolism, Pyruvate metabolism and the Citrate cycle (TCA cycle) were found to play an important role in energy metabolism, and some substrates could be used in the sperm medium for storage and cryopreservation.
HostingRepository	PRIDE
AnnounceDate	2017-10-31
AnnouncementXML	Submission_2017-10-31_03:19:35.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD006108
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	jingjing huang
SpeciesList	scientific name: Acipenser baerii x Acipenser schrenckii; NCBI TaxID: 1358430; scientific name: Acipenser; NCBI TaxID: 7901;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue; deaminated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600+

Revision	Datetime	Status	ChangeLog Entry
0	2017-03-17 04:47:31	ID requested
⏵ 1	2017-10-31 03:19:36	announced

Li P, Guo W, Yue H, Li C, Du H, Qiao X, Liu Z, Zhou Q, Wei Q, Variability in the protein profiles in spermatozoa of two sturgeon species. PLoS One, 12(10):e0186003(2017) [pubmed]

curator keyword: Biological

submitter keyword: iTRAQ

proteomics

spermatozoa

sturgeon

biomarker

Ping Li
contact affiliation	Key Laboratory of Freshwater Biodiversity Conservation, Ministry of Agriculture of China, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China
contact email	liping@yfi.ac.cn
lab head
jingjing huang
contact affiliation	genedenovo
contact email	jjhuang@genedenovo.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/10/PXD006108

PRIDE project URI

• PRIDE
  1. PXD006108
     1. Label: PRIDE project
     2. Name: Predictive biomarkers of sperm quality in sturgeon spermatozoa