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PXD006108

PXD006108 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePredictive biomarkers of sperm quality in sturgeon spermatozoa
DescriptionIn this study, we used the iTRAQ proteomics approach to perform proteomic profiling of spermatozoa associated with sperm quality in sturgeons. The results showed 291 and 359 differentially expressed proteins in A. baerii and A. schrenckii, respectively, of which 72 were common to both species and all were upregulated in high quality compared with low quality samples. The differentially expressed proteins were mainly categorized into the generation of precursor metabolites and energy and oxidation, and they were localized to the mitochondria. Three distinguishing pathways, Arginine and proline metabolism, Pyruvate metabolism and the Citrate cycle (TCA cycle) were found to play an important role in energy metabolism, and some substrates could be used in the sperm medium for storage and cryopreservation.
HostingRepositoryPRIDE
AnnounceDate2017-10-31
AnnouncementXMLSubmission_2017-10-31_03:19:35.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD006108
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterjingjing huang
SpeciesList scientific name: Acipenser baerii x Acipenser schrenckii; NCBI TaxID: 1358430; scientific name: Acipenser; NCBI TaxID: 7901;
ModificationListiTRAQ8plex-116 reporter+balance reagent acylated residue; deaminated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentTripleTOF 5600+
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-03-17 04:47:31ID requested
12017-10-31 03:19:36announced
Publication List
Li P, Guo W, Yue H, Li C, Du H, Qiao X, Liu Z, Zhou Q, Wei Q, Variability in the protein profiles in spermatozoa of two sturgeon species. PLoS One, 12(10):e0186003(2017) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: iTRAQ
proteomics
spermatozoa
sturgeon
biomarker
Contact List
Ping Li
contact affiliationKey Laboratory of Freshwater Biodiversity Conservation, Ministry of Agriculture of China, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China
contact emailliping@yfi.ac.cn
lab head
jingjing huang
contact affiliationgenedenovo
contact emailjjhuang@genedenovo.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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