PXD006108 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Predictive biomarkers of sperm quality in sturgeon spermatozoa |
Description | In this study, we used the iTRAQ proteomics approach to perform proteomic profiling of spermatozoa associated with sperm quality in sturgeons. The results showed 291 and 359 differentially expressed proteins in A. baerii and A. schrenckii, respectively, of which 72 were common to both species and all were upregulated in high quality compared with low quality samples. The differentially expressed proteins were mainly categorized into the generation of precursor metabolites and energy and oxidation, and they were localized to the mitochondria. Three distinguishing pathways, Arginine and proline metabolism, Pyruvate metabolism and the Citrate cycle (TCA cycle) were found to play an important role in energy metabolism, and some substrates could be used in the sperm medium for storage and cryopreservation. |
HostingRepository | PRIDE |
AnnounceDate | 2017-10-31 |
AnnouncementXML | Submission_2017-10-31_03:19:35.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD006108 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | jingjing huang |
SpeciesList | scientific name: Acipenser baerii x Acipenser schrenckii; NCBI TaxID: 1358430; scientific name: Acipenser; NCBI TaxID: 7901; |
ModificationList | iTRAQ8plex-116 reporter+balance reagent acylated residue; deaminated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | TripleTOF 5600+ |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-03-17 04:47:31 | ID requested | |
⏵ 1 | 2017-10-31 03:19:36 | announced | |
Publication List
Li P, Guo W, Yue H, Li C, Du H, Qiao X, Liu Z, Zhou Q, Wei Q, Variability in the protein profiles in spermatozoa of two sturgeon species. PLoS One, 12(10):e0186003(2017) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: iTRAQ |
proteomics |
spermatozoa |
sturgeon |
biomarker |
Contact List
Ping Li |
contact affiliation | Key Laboratory of Freshwater Biodiversity Conservation, Ministry of Agriculture of China, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China |
contact email | liping@yfi.ac.cn |
lab head | |
jingjing huang |
contact affiliation | genedenovo |
contact email | jjhuang@genedenovo.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD006108
- Label: PRIDE project
- Name: Predictive biomarkers of sperm quality in sturgeon spermatozoa