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PXD006101

PXD006101 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleChlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host pathogen interactions
DescriptionTo identify potential chlamydia genes that were regulated by the transcriptional enhancer chxR, we did a full proteome analysis of HeLa cells infected with the three independent chxR mutants. This lead to the discovery of a common set of five proteins (CT005, CT214, CT565, CT694, CT695) that were significantly down regulated in all three mutants, suggesting that their expression was regulated by chxR. Importantly, each of the five were free of any mutations and thus were not direct targets of the EMS treatment.
HostingRepositoryMassIVE
AnnounceDate2017-03-15
AnnouncementXMLSubmission_2017-03-15_16:48:57.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJulie Chih-yu Chen
SpeciesList scientific name: Chlamydia trachomatis; NCBI TaxID: 813; scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListCarbamidomethyl; TMT6plex
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-03-15 15:08:03ID requested
12017-03-15 16:48:58announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: chxR
Contact List
Grant McClarty
contact affiliationPublic Health Agency of Canada
contact emailgrant.mcclarty@phac-aspc.gc.ca
lab head
Julie Chih-yu Chen
contact affiliationPHAC NML Canada
contact emailchih-yu.chen@canada.ca
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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