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PXD006053

PXD006053 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMulti-omics analysis of β-catenin oncogenic networks
DescriptionWe used interaction and expression proteomic techniques in conjunction with RNA-Seq transcriptomic analysis to analyse how a β-catenin stabilizing mutation alters molecular networks in colorectal cancer cells. Integrated computational analyses of allowed us to identify significantly altered sub-networks linked to β-catenin oncogenesis.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:08:36.181.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRob Ewing
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-03-08 02:10:35ID requested
12018-05-18 04:09:50announced
22024-10-22 04:08:42announced2024-10-22: Updated project metadata.
Publication List
Ewing RM, Song J, Gokulrangan G, Bai S, Bowler EH, Bolton R, Skipp P, Wang Y, Wang Z, -Catenin Molecular Networks. J Proteome Res, 17(6):2216-2225(2018) [pubmed]
10.1021/acs.jproteome.8b00180;
Keyword List
curator keyword: Biomedical
submitter keyword: Human, HCT116, colorectal cancer
Contact List
Rob Ewing
contact affiliationBiological Sciences, University of Southampton
contact emailrob.ewing@soton.ac.uk
lab head
Rob Ewing
contact affiliationUniv Southampton
contact emailrob.ewing@soton.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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