PXD005989

PXD005989 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Post-translational modifications of vaccine candidates of Cryptosporidium parvum
Description	Here we describe the post translational modifications on vaccine candidate proteins from Cryptosporidium parvum. We have identified O-glycosylated peptides from GP15, GP40, GP900, and a novel mucin-like protein referred to as GP20. In addition, we have discovered that the immune dominant antigen, CP23, contains both N-myristoyl and C-palmitoyl modifications on the N-terminal region of the protein.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:36:31.715.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD005989
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	John Haserick
SpeciesList	scientific name: Cryptosporidium parvum; NCBI TaxID: 5807;
ModificationList	Myristoyl; HexNAc; Carbamidomethyl; Palmitoyl
Instrument	LTQ Orbitrap XL ETD; Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-02-28 08:25:41	ID requested
1	2017-08-14 02:01:45	announced
⏵ 2	2024-10-22 04:36:39	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD005989;
10.1371/journal.pone.0182395;
Haserick JR, Klein JA, Costello CE, Samuelson J, Cryptosporidium parvum vaccine candidates are incompletely modified with O-linked-N-acetylgalactosamine or contain N-terminal N-myristate and S-palmitate. PLoS One, 12(8):e0182395(2017) [pubmed]

10.6019/PXD005989;

10.1371/journal.pone.0182395;

Haserick JR, Klein JA, Costello CE, Samuelson J, Cryptosporidium parvum vaccine candidates are incompletely modified with O-linked-N-acetylgalactosamine or contain N-terminal N-myristate and S-palmitate. PLoS One, 12(8):e0182395(2017) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Cryptosporidium parvum, lipopeptides, vaccine candidates, glycopeptides, LC-MS/MS

curator keyword: Biomedical

submitter keyword: Cryptosporidium parvum, lipopeptides, vaccine candidates, glycopeptides, LC-MS/MS

Contact List

Catherine E. Costello
contact affiliation	Center for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, USA
contact email	cecmsms@bu.edu
lab head
John Haserick
contact affiliation	Boston University
contact email	haserick@bu.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/08/PXD005989
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/08/PXD005989

PRIDE project URI

Repository Record List

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