PXD005842

PXD005842 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The comparison of mitochondrial proteomics of fungal ETC Complex I mutant
Description	Candidiasis is the most common invasive fungal infection in clinical sets. The causative agent C. albicans has a complex metabolism for energy production in which mitochondria play important roles for its virulence to the host. Three fungal- specific mitochondrial ETC complex CI subunits - Goa1p, Nuo1p (Nuxm) and Nuo2p (NUZM) have been associated with assembly of CI and mitochondrial function in this organism. They also carry on a number of cellular bioprocess including cell wall mannan. To better understand the biological functions of each subunit, we profile the proteomics of three gene knockout mutants, by comparison with one from wild type (SN250). We hypothesize the common and CI subunit- specific cellular activities which are bound to mitochondrial CI in this organism.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:36:05.263.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	jing wang
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-02-03 04:51:58	ID requested
1	2017-08-16 00:36:27	announced
⏵ 2	2024-10-22 04:36:13	announced	2024-10-22: Updated project metadata.

Publication List

She X, Zhang P, Gao Y, Zhang L, Wang Q, Chen H, Calderone R, Liu W, Li D, A mitochondrial proteomics view of complex I deficiency in Candida albicans. Mitochondrion, 38():48-57(2018) [pubmed]
10.1016/j.mito.2017.08.003;

She X, Zhang P, Gao Y, Zhang L, Wang Q, Chen H, Calderone R, Liu W, Li D, A mitochondrial proteomics view of complex I deficiency in Candida albicans. Mitochondrion, 38():48-57(2018) [pubmed]

10.1016/j.mito.2017.08.003;

Keyword List

submitter keyword: proteomics, Oribtrap Fusion MS- nano-scaled liquid chromatography, mitochondria, and Candida albicans

submitter keyword: proteomics, Oribtrap Fusion MS- nano-scaled liquid chromatography, mitochondria, and Candida albicans

Contact List

xiaodongshe
contact affiliation	Institute of dermatology, Chinese academy of medical sciences
contact email	shexd1979@163.com
lab head
jing wang
contact affiliation	suzhou bionovogene
contact email	jingwang@bionovogene.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/08/PXD005842
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/08/PXD005842

PRIDE project URI

Repository Record List

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