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PXD005833

PXD005833 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe Proteomic Fingerprint of Prostate Cancer in Primary Tumors and Recurrent Lymph Node Metastases
DescriptionWe performed a quantitative proteome comparison on formalin-fixed paraffin embedded (FFPE) tissue of metastasized and non-metastasized primary prostate cancer (PCa) and on recurrent lymph node metastases. Comparing these three sample groups, we aimed to identify proteins, that might potentially promote/supress tumor progression or metastasis formation. Proteins were quantified label-free. Proteins with interesting biological functions were followed-up by immunohistochemistry.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:36:07.912.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAnn-Kathrin Müller
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-02-02 00:27:11ID requested
12017-12-19 02:43:11announced
22024-10-22 04:36:16announced2024-10-22: Updated project metadata.
Publication List
M, ü, ller AK, F, ö, ll M, Heckelmann B, Kiefer S, Werner M, Schilling O, Biniossek ML, Jilg CA, Drendel V, Proteomic Characterization of Prostate Cancer to Distinguish Nonmetastasizing and Metastasizing Primary Tumors and Lymph Node Metastases. Neoplasia, 20(2):140-151(2018) [pubmed]
10.1016/j.neo.2017.10.009;
Keyword List
curator keyword: Biomedical
submitter keyword: Lymph node metastases, shotgun proteomics, immunohistochemistry,Prostate Cancer, label free
Contact List
Oliver Schilling
contact affiliationInsitute for Molecular Medicine and Cell Research, University of Freiburg, Germany
contact emailoliver.schilling@mol-med.uni-freiburg.de
lab head
Ann-Kathrin Müller
contact affiliationAlbert-Ludwigs-Universität Freiburg
contact emailmuellerannka@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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