PXD005819
PXD005819 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of human anterior pituitary gland |
Description | The regulation of pituitary function via the hypothalamus and via intra-pituitary connections represents a complex system. Though hormones secreted from the pituitary glands have been well studied, overall information of proteins expressed in the pituitary glands is very limited. Protein expression profiling of normal pituitary tissue may lead to discovery of novel proteins playing an important role in the physiology of pituitary glands and can lead to better understanding of pituitary gland diseases. We aimed to carry out systematic proteomic profiling of adenohypophysis from human pituitary glands using high-resolution Fourier transform mass spectrometer. A total of 2,175 proteins were identified in this study of which, 105 proteins were identified for the first time as compared to high throughput proteomic-based studies from human pituitary glands. The comprehensive list of proteins identified in this study will facilitate the better understanding the role of this important gland in health and disease. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:35:52.932.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Keshava Prasad T. S. |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2017-02-01 00:50:54 | ID requested | |
1 | 2019-01-02 02:08:15 | announced | |
⏵ 2 | 2024-10-22 04:35:53 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1089/omi.2018.0160; |
Yelamanchi SD, Tyagi A, Mohanty V, Dutta P, Korbonits M, Chavan S, Advani J, Madugundu AK, Dey G, Datta KK, Rajyalakshmi M, Sahasrabuddhe NA, Chaturvedi A, Kumar A, Das AA, Ghosh D, Jogdand GM, Nair HH, Saini K, Panchal M, Sarvaiya MA, Mohanraj SS, Sengupta N, Saxena P, Subramani PA, Kumar P, Akkali R, Reshma SV, Santhosh RS, Rastogi S, Kumar S, Ghosh SK, Irlapati VK, Srinivasan A, Radotra BD, Mathur PP, Wong GW, Satishchandra P, Chatterjee A, Gowda H, Bhansali A, Pandey A, Shankar SK, Mahadevan A, Prasad TSK, Proteomic Analysis of the Human Anterior Pituitary Gland. OMICS, 22(12):759-769(2018) [pubmed] |
Keyword List
submitter keyword: Adenohypophysis,Anterior pituitary gland, Proteomics |
Contact List
T. S. Keshava Prasad | |
---|---|
contact affiliation | Institue of Bioinformatics Discoverer Building, 7th Floor International Tech Park Whitefield, Bangalore - 560 066 Karnataka, India. |
contact email | keshav@ibioinformatics.org |
lab head | |
Keshava Prasad T. S. | |
contact affiliation | Institute of Bioinformatics, Bangalore, Karnataka, India. |
contact email | keshav@ibioinformatics.org |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD005819 |
PRIDE project URI |
Repository Record List
[ + ]