PXD005755

PXD005755 is an original dataset announced via ProteomeXchange.

Title	Human serum proteome dynamics in type 2 diabetes using heavy water labeling mass spectrometry
Description	Control subjects and type 2 diabetic patients were given deuterium-labeled (heavy) water for a seven-day period and their plasma serum proteins were analyzed by high-resolution mass spectrometry. Using an in-house-developed software, fractional synthesis rates were calculated for proteins of interest. These data can be used for qualitative, quantitative, and kinetics study of human serum proteins under healthy and type 2 diabetes conditions.
HostingRepository	PRIDE
AnnounceDate	2017-11-02
AnnouncementXML	Submission_2018-03-14_01:42:45.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD005755
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Takhar Kasumov
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2017-01-20 05:28:59	ID requested
1	2017-11-02 03:29:55	announced
⏵ 2	2018-03-14 01:42:46	announced	Updated publication reference for PubMed record(s): 29079528.

Golizeh M, Lee K, Ilchenko S, Ö, sme A, Bena J, Sadygov RG, Kashyap SR, Kasumov T, Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes. Free Radic Biol Med, 113():461-469(2017) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: human, serum, proteome dynamics, heavy water, mass spectrometry, type 2 diabetes, T2D

Takhar Kasumov
contact affiliation	Department of Pharmaceutical Sciences, Northeast Ohio Medical University, United States
contact email	tkasumov@neomed.edu
lab head
Takhar Kasumov
contact affiliation	NEOMED
contact email	tkasumov@neomed.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/11/PXD005755

PRIDE project URI

• PRIDE
  1. PXD005755
     1. Label: PRIDE project
     2. Name: Human serum proteome dynamics in type 2 diabetes using heavy water labeling mass spectrometry