PXD005679

PXD005679 is an original dataset announced via ProteomeXchange.

Title	Proteome expression changes upon Halofuginone treatment
Description	NHCF-V primary cardiac fibroblasts where treated for 24 hours with either 1) 100nM Halofuginone (TMT labels 126 and 129L) 2) 300nM Halofuginone (TMT labels 127L and 129H) 3) 300 nM Halofuginone + 4 mM L-Pro (TMT labels 127H and 130L) 4) DMSO (TMT labels 128H and 131)
HostingRepository	PRIDE
AnnounceDate	2019-03-06
AnnouncementXML	Submission_2019-03-06_02:11:12.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Maria Faelth Savitski
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2017-01-10 01:37:48	ID requested
1	2017-05-16 06:10:03	announced
2	2017-06-20 05:44:58	announced	Updated project metadata.
3	2017-10-24 04:54:21	announced	Updated project metadata.
⏵ 4	2019-03-06 02:11:13	announced	Updated project metadata.

Qin P, Arabacilar P, Bernard RE, Bao W, Olzinski AR, Guo Y, Lal H, Eisennagel SH, Platchek MC, Xie W, Del Rosario J, Nayal M, Lu Q, Roethke T, Schnackenberg CG, Wright F, Quaile MP, Halsey WS, Hughes AM, Sathe GM, Livi GP, Kirkpatrick RB, Qu XA, Rajpal DK, Faelth Savitski M, Bantscheff M, Joberty G, Bergamini G, Force TL, Gatto GJ, Hu E, Willette RN, Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress. J Am Heart Assoc, 6(5):(2017) [pubmed]

curator keyword: Biomedical

submitter keyword: human, halofuginone, primary cardiac fibroblasts

Marcus Bantscheff
contact affiliation	Cellzome GmbH, Heidelberg, Germany
contact email	marcus.bantscheff@cellzome.com
lab head
Maria Faelth Savitski
contact affiliation	Cellzome
contact email	maria.x.faelth-savitski@gsk.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/05/PXD005679

PRIDE project URI

• PRIDE
  1. PXD005679
     1. Label: PRIDE project
     2. Name: Proteome expression changes upon Halofuginone treatment