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PXD005648

PXD005648 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of eleven tissues of Chinese Giant Salamander (Andrias davidianus)
DescriptionThe Chinese giant salamander (CGS, Andrias davidianus) is the largest and longest-lived amphibian. Global and quantitative proteome analysis of multiple tissues would indicate tissue-specific mechanisms and investigate the function of each protein from a whole-organism perspective. Herein, this study performed proteome analysis of eleven tissues collected from adult female CGS using isobaric tags for relative and absolute quantitation (iTRAQ) coupled with LC-MS/MS methods. Based on the predicted protein database from CGS transcriptome database previously obtained, we identified a total of 4607 proteins with quantitative information. Among them, 2153 proteins were shared by two iTRAQ 8-plex experiments with liver as common sample, and these proteins were used for subsequent analysis. Our data will be useful for future research into this large-genome species, as well as for vertebrate-wide comparative genomic, transcriptomic and proteomic studies.
HostingRepositoryPRIDE
AnnounceDate2019-11-18
AnnouncementXMLSubmission_2019-11-18_01:33:03.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmittercunshuan xu
SpeciesList scientific name: Andrias davidianus; NCBI TaxID: 141262;
ModificationListiTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-01-03 05:23:54ID requested
12019-11-18 01:33:04announced
Publication List
Geng X, Guo J, Zang X, Chang C, Shang H, Wei H, Xu C, Proteomic analysis of eleven tissues in the Chinese giant salamander (Andrias davidianus). Sci Rep, 9(1):16415(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Chinese Giant Salamander (Andrias davidianus), Organ tissue, iTRAQ, LC-MS/MS
Contact List
Cunshuan Xu
contact affiliationState Key Laboratory Cultivation Base for Cell Differentiation Regulation, Henan Normal University, Xinxiang, Henan Province, China
contact emailcellkeylab@126.com
lab head
cunshuan xu
contact affiliationhenan normal university
contact emailcellkeylab@126.com
dataset submitter
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Dataset FTP location
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