PXD005627 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Serine ADP-ribosylation depends on HPF1 |
Description | We report that serine ADPr is strictly dependent on HPF1 (histone PARylation factor 1. Quantitative proteomics revealed that serine ADPr does not occur in cells lacking HPF1. We identified three endogenous serine ADPr sites are located on the PARP-1 automodification domain. Further identification of serine ADPr on hundreds of other targets indicates that serine ADPr is a widespread modification. |
HostingRepository | PRIDE |
AnnounceDate | 2017-02-10 |
AnnouncementXML | Submission_2017-02-14_03:33:54.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Juan Jose Bonfiglio |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | adenosine diphosphoribosyl (ADP-ribosyl) modified residue |
Instrument | Q Exactive HF; Orbitrap Fusion ETD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-01-02 01:33:14 | ID requested | |
1 | 2017-02-10 02:42:14 | announced | |
⏵ 2 | 2017-02-14 03:33:55 | announced | Updated publication reference for PubMed record(s): 28190768. |
Publication List
Bonfiglio JJ, Fontana P, Zhang Q, Colby T, Gibbs-Seymour I, Atanassov I, Bartlett E, Zaja R, Ahel I, Matic I, Serine ADP-Ribosylation Depends on HPF1. Mol Cell, 65(5):932-940.e6(2017) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: ADP-ribosylation |
HPF1 |
PARP-1 |
PARP-2 |
histones |
proteomics |
Contact List
Ivan Matic |
contact affiliation | CECAD Research Group Leader, Max Planck Institute for Biology of Ageing, Cologne, Germany |
contact email | imatic@age.mpg.de |
lab head | |
Juan Jose Bonfiglio |
contact affiliation | CECAD Research Group, Max Planck Institute for Biology of Ageing, Cologne, Germany |
contact email | jbonfiglio@age.mpg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/02/PXD005627 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005627
- Label: PRIDE project
- Name: Serine ADP-ribosylation depends on HPF1