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PXD005618

PXD005618 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleC elegans Proteomics
DescriptionReactive Oxygen Species increase gradually with aging and Steadily diminish the cell's ability to maintain homeostasis. Nuclear Factor-like 2 and its C elegans ortholog, SKN-1 are transcription factors that play a pivotal role in oxidative stress response, cellular homeostasis and lifespan. But like other defence systems, Nrf2-mediated stress response is compromised in aging and neurodegenerative diseases. In this study we provide evidence that an FDA-approved drug is a bona fide activator of Nrf2/SKN-1 pathway.
HostingRepositoryMassIVE
AnnounceDate2016-12-21
AnnouncementXMLSubmission_2016-12-21_14:08:52.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAmirmansoor Hakimi
SpeciesList scientific name: Caenorhabditis elegans; NCBI TaxID: 6239; scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListCarbamidomethyl; Oxidation
InstrumentOrbitrap Fusion ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-12-21 12:19:39ID requested
12016-12-21 14:08:53announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: c Elegans, SILAC, Label-free, Proteomics
Contact List
principal_investigator
lab head
Amirmansoor Hakimi
contact affiliationUTSW
contact emailamirmansoor.hakimi@utsouthwestern.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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