PXD005618
PXD005618 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | C elegans Proteomics |
Description | Reactive Oxygen Species increase gradually with aging and Steadily diminish the cell's ability to maintain homeostasis. Nuclear Factor-like 2 and its C elegans ortholog, SKN-1 are transcription factors that play a pivotal role in oxidative stress response, cellular homeostasis and lifespan. But like other defence systems, Nrf2-mediated stress response is compromised in aging and neurodegenerative diseases. In this study we provide evidence that an FDA-approved drug is a bona fide activator of Nrf2/SKN-1 pathway. |
HostingRepository | MassIVE |
AnnounceDate | 2016-12-21 |
AnnouncementXML | Submission_2016-12-21_14:08:52.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Amirmansoor Hakimi |
SpeciesList | scientific name: Caenorhabditis elegans; NCBI TaxID: 6239; scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | Carbamidomethyl; Oxidation |
Instrument | Orbitrap Fusion ETD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2016-12-21 12:19:39 | ID requested | |
⏵ 1 | 2016-12-21 14:08:53 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: c Elegans, SILAC, Label-free, Proteomics |
Contact List
principal_investigator | |
---|---|
lab head | |
Amirmansoor Hakimi | |
contact affiliation | UTSW |
contact email | amirmansoor.hakimi@utsouthwestern.edu |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000080435 |