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PXD005550

PXD005550 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphoproteomic analysis of Bluetongue virus infection
DescriptionBluetongue virus causes infections in wild and domesticated ruminants, with the potential for causing significant morbidity, mortality and economic harm in both the developing and developed world. While vaccines have been developed, no treatment for acute infections exists. In this regard, a possible approach is to determine host-cell factors utilised by Bluetongue virus. We thus proceeded to characterize the phosphoproteome of BTV infected HeLa cells to elucidate the intracellular signalling pathways and identify critical host factors activated during Bluetongue virus infection.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:34:48.676.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEdward Emmott
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-12-12 05:40:28ID requested
12017-08-29 08:39:56announced
22019-02-12 08:13:44announcedUpdated publication reference for PubMed record(s): 28851738.
32024-10-22 04:34:50announced2024-10-22: Updated project metadata.
Publication List
Mohl BP, Emmott E, Roy P, Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection. Mol Cell Proteomics, 16(11):1990-2005(2017) [pubmed]
10.1074/mcp.M117.067355;
Keyword List
curator keyword: Biomedical
submitter keyword: Bluetongue, Orbivirus, dsRNA, SILAC, Reovirus, phosphoproteomics
Contact List
Polly Roy
contact affiliationFaculty of Infectious and Tropical Diseases, London School of Hygene & Tropical Medicine, London, UK.
contact emailpolly.roy@lshtm.ac.uk
lab head
Edward Emmott
contact affiliationNortheastern University
contact emaile.emmott@northeastern.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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