PXD005521

PXD005521 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic characterization of stem cell-derived extracellular matrices
Description	We characterized and compared the proteomic composition of ECM produced in vitro by bone marrow-derived MSC, adipose-derived MSC and neonatal fibroblasts isolated from different donors, employing a multidimensional proteomic approach coupled with label-based quantitative proteomics. Each cell-derived ECM displayed a specific and unique matrisome signature, yet they all shared a common set of proteins. We evaluated the biological response of cells cultured on the different matrices and compared them to cells on standard TCPS. The matrices lead to differential proliferation and gene expression profiles between the cell types and as compared to TCPS, indicating that the cell-derived ECM influence each cell type in a unique manner.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:34:16.465.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD005521
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Amanda Del Rosario
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Deamidated; Oxidation; Carbamyl; Gln->pyro-Glu
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-12-07 05:30:14	ID requested
1	2017-03-08 08:25:44	announced
⏵ 2	2024-10-22 04:34:16	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD005521;

10.6019/PXD005521;

Keyword List

curator keyword: Biomedical
submitter keyword: LC-MS-MS, human,ECM

curator keyword: Biomedical

submitter keyword: LC-MS-MS, human,ECM

Contact List

Amanda Del Rosario
contact affiliation	Massachusetts Institute of Technology
contact email	aweaver@mit.edu
lab head
Amanda Del Rosario
contact affiliation	Janssen Pharmaceuticals
contact email	adelros1@its.jnj.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/03/PXD005521
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/03/PXD005521

PRIDE project URI

Repository Record List

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