PXD005489

PXD005489 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones
Description	Histones and histone variants are essential components of the nuclear chromatin. While mass spectrometry has opened a large window to their characterization and functional studies, their identification from proteomic data remains challenging. Indeed, the current interpretation of mass spectrometry data relies on public databases which are either not exhaustive (Swiss-Prot) or contain many redundant entries (UniProtKB or NCBI). Currently, no protein database is ideally suited for the analysis of histones and the complex array of mammalian histone variants. Here, we propose two proteomics-oriented manually curated databases for mouse and human histone variants. Several histone variants, which had so far only been inferred by homology or detected at the RNA level, were detected by mass spectrometry, confirming the existence of their protein form.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:34:17.061.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD005489
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Delphine PFLIEGER
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Propionyl; Methyl; Dimethyl; Acetyl; Carbamidomethyl
Instrument	LTQ Orbitrap Velos; Q Exactive; LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-12-02 05:07:01	ID requested
1	2017-01-11 04:57:59	announced
2	2017-01-17 07:38:09	announced	Updated project metadata.
3	2017-01-19 23:53:58	announced	Updated project metadata.
⏵ 4	2024-10-22 04:34:18	announced	2024-10-22: Updated project metadata.

Publication List

10.1186/s13072-016-0109-x;
10.6019/PXD005489;
El Kennani S, Adrait A, Shaytan AK, Khochbin S, Bruley C, Panchenko AR, Landsman D, Pflieger D, Govin J, MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones. Epigenetics Chromatin, 10():2(2017) [pubmed]

10.1186/s13072-016-0109-x;

10.6019/PXD005489;

El Kennani S, Adrait A, Shaytan AK, Khochbin S, Bruley C, Panchenko AR, Landsman D, Pflieger D, Govin J, MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones. Epigenetics Chromatin, 10():2(2017) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: proteomics, mass spectrometry,Histone, chromatin, histone variants

curator keyword: Biological

submitter keyword: proteomics, mass spectrometry,Histone, chromatin, histone variants

Contact List

Christophe Bruley
contact affiliation	CEA
contact email	christophe.bruley@cea.fr
lab head
Delphine PFLIEGER
contact affiliation	CNRS
contact email	delphine.pflieger@cea.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/01/PXD005489
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/01/PXD005489

PRIDE project URI

Repository Record List

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