PXD005482

PXD005482 is an original dataset announced via ProteomeXchange.

Title	Analysis of Trpc6 Phosphorylation in HEK293T cells
Description	The aim of this project was to detect phosphorylation on the human calcium Channel TRPC6. TRPC6 is mutated in genetic diseases of the podocyte, a postmitotic cell at the epithelial filtration barrier
HostingRepository	PRIDE
AnnounceDate	2017-08-23
AnnouncementXML	Submission_2017-09-12_03:36:26.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Markus Rinschen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2016-12-01 05:37:16	ID requested
1	2017-08-23 01:25:13	announced
⏵ 2	2017-09-12 03:36:27	announced	Updated publication reference for PubMed record(s): 28877958.

Hagmann H, Mangold N, Rinschen MM, Koenig T, Kunzelmann K, Schermer B, Benzing T, Brinkkoetter PT, Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression. FASEB J, 32(1):208-219(2018) [pubmed]

curator keyword: Biological

submitter keyword: HEK293T cells, Trpc6, phosphorylation

Henning Hagmann
contact affiliation	University Hospital Cologne
contact email	Henning.Hagmann@uk-koeln.de
lab head
Markus Rinschen
contact affiliation	Kidney research center cologne
contact email	markus.rinschen@uk-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/08/PXD005482

PRIDE project URI

• PRIDE
  1. PXD005482
     1. Label: PRIDE project
     2. Name: Analysis of Trpc6 Phosphorylation in HEK293T cells