PXD005462

PXD005462 is an original dataset announced via ProteomeXchange.

Title	Histone ADP Ribosylation - Serine is a new target residue for endogenous ADP-ribosylation on histones
Description	ADPr sites on histones obtained from cells were directly identified. We have identified 12 unique ADPr sites in human osteosarcoma cells and report serine ADPr as a new type of histone mark that responds to DNA damage.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:34:09.277.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Colby
SpeciesList	scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; adenosine diphosphoribosyl (ADP-ribosyl) modified residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion ETD

Revision	Datetime	Status	ChangeLog Entry
0	2016-11-30 00:40:41	ID requested
1	2016-12-22 04:21:59	announced
2	2017-10-24 03:15:04	announced	Updated project metadata.
⏵ 3	2024-10-22 04:34:10	announced	2024-10-22: Updated project metadata.

10.1038/nchembio.2180;

Leidecker O, Bonfiglio JJ, Colby T, Zhang Q, Atanassov I, Zaja R, Palazzo L, Stockum A, Ahel I, Matic I, Serine is a new target residue for endogenous ADP-ribosylation on histones. Nat Chem Biol, 12(12):998-1000(2016) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: ADPR,Histones, serine, ADP Ribosylation

Ivan Matic
contact affiliation	CECAD group leader
contact email	imatic@age.mpg.de
lab head
Thomas Colby
contact affiliation	MPI for Biology of Ageing
contact email	colby@age.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD005462

PRIDE project URI

• PRIDE
  1. PXD005462
     1. Label: PRIDE project
     2. Name: Histone ADP Ribosylation - Serine is a new target residue for endogenous ADP-ribosylation on histones