PXD005435

PXD005435 is an original dataset announced via ProteomeXchange.

Title	Bottlenose Dolphin Plasma Proteome
Description	This study was designed to characterize and evaluate the proteome in plasma samples collected before and after a public swim interaction involving four male (2 to 6 y) aquarium-based bottlenose dolphins (Tursiops truncatus). Blood samples were collected from the tail flukes appoximately 15 min before (n=4 samples) and 15 min after (n=4 samples) the first swim interaction of the day, which was reinforced by a regularly scheduled feeding regimen. Samples were subjected to liquid chromatography-tandem mass spectrometry (LC-MS/MS) as well as conventional clinical biochemistry analysis. Mass spectra data were used to search the NCBI database restricted to Tursiops truncatus which resulted in the identification of 196 unique proteins with a broad range of functional roles based on manual GO analysis. Differential regulation of proteins was based on log2 mean fold change (FC) and statistical probability such that the abundance of lysozyme (FC -1.2036; P<0.058) an immune-related protein and flavin reductase (FC -0.9702; P<0.004) a metabolic-related protein were highest before compared to after the swim interaction. Both proteins decreased by 58 and 52%, respectively.
HostingRepository	PRIDE
AnnounceDate	2019-03-22
AnnouncementXML	Submission_2019-03-22_05:16:16.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Blake Miller
SpeciesList	scientific name: Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus); NCBI TaxID: 9739;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-11-24 01:14:08	ID requested
⏵ 1	2019-03-22 05:16:17	announced

Dataset with its publication pending

curator keyword: Biological

submitter keyword: Bottlenose, Dolphin, Plasma, Tursiops

Paolo Nanni
contact affiliation	Functional Genomics Center of Zurich, Switzerland
contact email	paolo.nanni@fgcz.uzh.ch
lab head
Blake Miller
contact affiliation	Ross University School of Veterinary Medicine
contact email	blakemiller@students.rossu.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/03/PXD005435

PRIDE project URI

• PRIDE
  1. PXD005435
     1. Label: PRIDE project
     2. Name: Bottlenose Dolphin Plasma Proteome