PXD005384

PXD005384 is an original dataset announced via ProteomeXchange.

Title	equine CD4+ T cells show changed membrane protein expression in autoimmune uveitis
Description	Through this comparative proteomic study of equine CD4+ cells 376 membrane proteins could be identified. Several proteins showed changed abundance in horses affected by a spontaneous autoimmune disease (equine recurrent uveitis, ERU). Findings provide novel knowledge about changes in the CD4+ immune cell membrane proteome in a spontaneously and naturally occurring autoimmune disease in horses. The data is highly relevant for veterinary medicine and has proven translational quality for autoimmune uveitis in man.
HostingRepository	PRIDE
AnnounceDate	2017-10-24
AnnouncementXML	Submission_2017-10-24_04:41:45.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Roxane Degroote
SpeciesList	scientific name: Equus caballus (Horse); NCBI TaxID: 9796;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap XL

Revision	Datetime	Status	ChangeLog Entry
0	2016-11-17 05:29:36	ID requested
1	2017-01-09 08:03:34	announced
⏵ 2	2017-10-24 04:41:46	announced	Updated project metadata.

Degroote RL, Uhl PB, Amann B, Krackhardt AM, Ueffing M, Hauck SM, Deeg CA, Formin like 1 expression is increased on CD4+ T lymphocytes in spontaneous autoimmune uveitis. J Proteomics, 154():102-108(2017) [pubmed]

curator keyword: Biomedical

submitter keyword: CD4+ T cells, membrane proteins, LC-MSMS mass spectrometry analysis, autoimmune uveitis, equine recurrent uveitis

Cornelia Annette Deeg
contact affiliation	Department of Veterinary Sciences, Ludwig-Maximilians-University of Munich, Munich, Germany Department of Experimental Ophthalmology, Philipps University of Marburg, Marburg, Germany
contact email	deeg@tiph.vetmed.uni-muenchen.de
lab head
Roxane Degroote
contact affiliation	Ludwig-Maximilians-University Munich, Dept. of Veterinary Sciences, Veterinaerstrasse 13, 80539, Munich, Germany
contact email	r.degroote@lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/01/PXD005384

PRIDE project URI

• PRIDE
  1. PXD005384
     1. Label: PRIDE project
     2. Name: equine CD4+ T cells show changed membrane protein expression in autoimmune uveitis