PXD005334

PXD005334 is an original dataset announced via ProteomeXchange.

Title	Anti-Warburg effect elicited by mitochondrial biogenesis drives differentiation of glioblastoma cells into astroglial cells
Description	Glioblastoma (GBM) is among the most aggressive of human cancers. Although differentiation therapy has been proposed to be potential approach to treat GBM, the mechanisms of induced differentiation remain poorly defined. Here, we established an induced differentiation model of GBM using cAMP activators, which specifically directed GBM into astroglia. We want to use transcriptomic and proteomic analyses to uncover the central regulators of induced differentiation in solid tumor.
HostingRepository	PRIDE
AnnounceDate	2017-01-17
AnnouncementXML	Submission_2017-01-16_16:31:34.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yizhao Luan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2016-11-14 02:16:33	ID requested
⏵ 1	2017-01-16 16:31:38	announced

Xing F, Luan Y, Cai J, Wu S, Mai J, Gu J, Zhang H, Li K, Lin Y, Xiao X, Liang J, Li Y, Chen W, Tan Y, Sheng L, Lu B, Lu W, Gao M, Qiu P, Su X, Yin W, Hu J, Chen Z, Sai K, Wang J, Chen F, Chen Y, Zhu S, Liu D, Cheng S, Xie Z, Zhu W, Yan G, Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes. Cell Rep, 18(2):468-481(2017) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: LC-MS/MS, Glioblastoma, Human

Guangmei Yan
contact affiliation	Sun Yat-sen university
contact email	ygm@mail.sysu.edu.cn
lab head
Yizhao Luan
contact affiliation	Sun Yat-sen university
contact email	luanyz_leo@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/01/PXD005334

PRIDE project URI

• PRIDE
  1. PXD005334
     1. Label: PRIDE project
     2. Name: Anti-Warburg effect elicited by mitochondrial biogenesis drives differentiation of glioblastoma cells into astroglial cells