PXD005333 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Delta-like ligand 4-Notch signaling inhibition regulates pancreatic islet function and insulin secretion |
Description | Dll4-Notch signaling is required for cell fate decisions and neoplasias. However, emerging evidence suggests a role for Dll4-Notch signaling in metabolic and immune diseases. To date, there is no evidence of a direct effect of Dll4-Notch signaling inhibition on pancreatic islet function and insulin secretion. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:16:34.923.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Antigoni Manousopoulou |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | phosphorylated residue; deaminated residue; monohydroxylated residue |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-11-14 01:59:41 | ID requested | |
1 | 2018-08-13 09:22:26 | announced | |
2 | 2019-02-12 08:12:31 | announced | Updated publication reference for PubMed record(s): 29386132. |
⏵ 3 | 2024-10-22 04:16:35 | announced | 2024-10-22: Updated project metadata. |
Publication List
Billiard F, Karaliota S, Wang B, Stellas D, Serafimidis I, Manousopoulou A, Koutmani Y, Ninou E, Golubov J, DaNave A, Tsakanikas P, Xin Y, Zhang W, Sleeman M, Yancopoulos GD, Murphy AJ, Garbis SD, Karalis K, Skokos D, Delta-like Ligand-4-Notch Signaling Inhibition Regulates Pancreatic Islet Function and Insulin Secretion. Cell Rep, 22(4):895-904(2018) [pubmed] |
10.1016/j.celrep.2017.12.076; |
Keyword List
curator keyword: Biomedical |
submitter keyword: GSIs, Dll4,diabetes |
Contact List
Spiros D. Garbis |
contact affiliation | University of Southampton |
contact email | S.D.Garbis@soton.ac.uk |
lab head | |
Antigoni Manousopoulou |
contact affiliation | Proteas Bioanalytics Inc. |
contact email | Antigoni.Manousopoulou@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005333
- Label: PRIDE project
- Name: Delta-like ligand 4-Notch signaling inhibition regulates pancreatic islet function and insulin secretion