PXD005237

PXD005237 is an original dataset announced via ProteomeXchange.

Title	Re-examining the role of Cdc14 phosphatase in mitotic exit
Description	Given that Cdc14 enzymes are so highly conserved, we questioned whether budding yeast Cdc14 could really have such a different influence on Cdk site dephosphorylation. We used quantitative phosphoproteomics to directly measure the in vivo specificity of budding yeast Cdc14 and found that it very selectively dephosphorylates a distinct sub-class of Cdk sites and does not catalyze widespread Cdk site dephosphorylation as widely believed.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:33:46.524.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Brendan Powers
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	phosphorylated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2016-10-28 07:05:53	ID requested
1	2017-07-13 05:14:22	announced
⏵ 2	2024-10-22 04:33:47	announced	2024-10-22: Updated project metadata.

Powers BL, Hall MC, Re-examining the role of Cdc14 phosphatase in reversal of Cdk phosphorylation during mitotic exit. J Cell Sci, 130(16):2673-2681(2017) [pubmed]

10.1242/jcs.201012;

curator keyword: Biological

submitter keyword: protein phosphatase, mitosis,Cdc14, cdk, mitotic exit, phosphoproteomics, cyclin-dependent kinase

Mark Hall
contact affiliation	Department of Biochemistry and Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907
contact email	mchall@purdue.edu
lab head
Brendan Powers
contact affiliation	Purdue University
contact email	powers14@purdue.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/07/PXD005237

PRIDE project URI

• PRIDE
  1. PXD005237
     1. Label: PRIDE project
     2. Name: Re-examining the role of Cdc14 phosphatase in mitotic exit