PXD005237 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Re-examining the role of Cdc14 phosphatase in mitotic exit |
Description | Given that Cdc14 enzymes are so highly conserved, we questioned whether budding yeast Cdc14 could really have such a different influence on Cdk site dephosphorylation. We used quantitative phosphoproteomics to directly measure the in vivo specificity of budding yeast Cdc14 and found that it very selectively dephosphorylates a distinct sub-class of Cdk sites and does not catalyze widespread Cdk site dephosphorylation as widely believed. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:33:46.524.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Brendan Powers |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | phosphorylated residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-10-28 07:05:53 | ID requested | |
1 | 2017-07-13 05:14:22 | announced | |
⏵ 2 | 2024-10-22 04:33:47 | announced | 2024-10-22: Updated project metadata. |
Publication List
Powers BL, Hall MC, Re-examining the role of Cdc14 phosphatase in reversal of Cdk phosphorylation during mitotic exit. J Cell Sci, 130(16):2673-2681(2017) [pubmed] |
10.1242/jcs.201012; |
Keyword List
curator keyword: Biological |
submitter keyword: protein phosphatase, mitosis,Cdc14, cdk, mitotic exit, phosphoproteomics, cyclin-dependent kinase |
Contact List
Mark Hall |
contact affiliation | Department of Biochemistry and Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907 |
contact email | mchall@purdue.edu |
lab head | |
Brendan Powers |
contact affiliation | Purdue University |
contact email | powers14@purdue.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/07/PXD005237 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005237
- Label: PRIDE project
- Name: Re-examining the role of Cdc14 phosphatase in mitotic exit