PXD005154 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | lncRNA MALAT1 interactome |
Description | Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA (lncRNA) that was first discovered as a prognostic marker for lung cancer metastasis. MALAT1 has been implicated in the tumorigenesis of numerous tumor types. To further delineate the underlying molecular mechanism, we established a high-throughput strategy to characterize the interacting proteins of MALAT1 by combining RNA pull down, quantitative proteomics, bioinformatics analysis, and experimental validation. |
HostingRepository | PRIDE |
AnnounceDate | 2018-10-26 |
AnnouncementXML | Submission_2018-10-26_13:29:50.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ruibing Chen |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-10-14 06:32:35 | ID requested | |
⏵ 1 | 2018-10-26 13:29:51 | announced | |
Publication List
Chen R, Liu Y, Zhuang H, Yang B, Hei K, Xiao M, Hou C, Gao H, Zhang X, Jia C, Li L, Li Y, Zhang N, Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation. Nucleic Acids Res, 45(17):9947-9959(2017) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: lncRNA, MALAT1, LC-MS/MS, RNA pulldown |
Contact List
Ruibing Chen |
contact affiliation | Tianjin Medical University |
contact email | chenruibing@tijmu.edu.cn |
lab head | |
Ruibing Chen |
contact affiliation | Tianjin Medical University |
contact email | chenruibing@tijmu.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD005154 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005154
- Label: PRIDE project
- Name: lncRNA MALAT1 interactome