PXD005152 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The antiviral protein IFIX is targeted for degradation during HSV-1 infection |
Description | IFIX has been shown to be an antiviral factor druing HSV-1 infection. Here we define a mechanism by which IFIX exerts it antiviral function and discover a means by which the virus target IFIX to inhibit this function. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:29:53.330.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD005152 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Marni Crow |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Ammonia-loss; Phospho; Dehydrated; Oxidation; Acetyl; Carbamidomethyl |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-10-14 06:25:30 | ID requested | |
1 | 2017-01-16 07:59:25 | announced | |
2 | 2017-01-17 07:36:43 | announced | Updated project metadata. |
⏵ 3 | 2024-10-22 04:30:28 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.6019/PXD005152; |
Crow MS, Cristea IM, Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation. Mol Cell Proteomics, 16(4 suppl 1):S200-S214(2017) [pubmed] |
10.1074/mcp.M116.064741; |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: HSV-1,IFIX |
Contact List
Ileana Cristea |
contact affiliation | Department of Molecular Biology, Princeton University |
contact email | icristea@princeton.edu |
lab head | |
Marni Crow |
contact affiliation | Princeton University |
contact email | marni@princeton.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/01/PXD005152 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005152
- Label: PRIDE project
- Name: The antiviral protein IFIX is targeted for degradation during HSV-1 infection