PXD005143

PXD005143 is an original dataset announced via ProteomeXchange.

Title	N-GlycositeAtlas, a database resource for mass spectrometry-based human N-linked glycoproteins and glycosylation sites
Description	N-Linked glycoprotein is a highly interesting class of proteins for clinical and biological research. The large-scale characterization of N-linked glycoproteins accomplished by mass spectrometry-based glycoproteomics has provided valuable insights into the interdependence of glycoprotein structure and protein function. However, these studies focus mainly on the analysis of specific sample type, and lack integration of each glycoproteomic data from different tissues, body fluids or cell types. In this study, we established N-GlycositeAtlas, a comprehensive database resource of human N-linked glycoproteins and their glycosylation sites identified by mass spectrometry. N-GlycositeAtlas contains more than 30,000 glycosite-containing peptides (representing >14,000 N-glycosylation sites) from more than 7,000 N-glycoproteins from different biological sources including human-derived tissues, body fluids and cell lines from over 100 studies. The entire human N-glycoproteome database as well as 22 sub-databases associated with individual tissues or body fluids can be downloaded from the N-GlycositeAtlas website at nglycositeatlas.biomarkercenter.org.
HostingRepository	PRIDE
AnnounceDate	2019-11-11
AnnouncementXML	Submission_2019-11-11_00:30:17.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shisheng Sun
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ4plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-10-13 02:21:22	ID requested
⏵ 1	2019-11-11 00:30:19	announced

Sun S, Hu Y, Ao M, Shah P, Chen J, Yang W, Jia X, Tian Y, Thomas S, Zhang H, -GlycositeAtlas: a database resource for mass spectrometry-based human N-linked glycoprotein and glycosylation site mapping. Clin Proteomics, 16():35(2019) [pubmed]

curator keyword: Biological

submitter keyword: glycoprotein, protein glycosylation, database, glycoproteome, mass spectrometry

Hui Zhang
contact affiliation	1Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
contact email	huizhang@jhu.edu
lab head
Shisheng Sun
contact affiliation	Johns Hopkins University
contact email	shisheng_sun@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/11/PXD005143

PRIDE project URI

• PRIDE
  1. PXD005143
     1. Label: PRIDE project
     2. Name: N-GlycositeAtlas, a database resource for mass spectrometry-based human N-linked glycoproteins and glycosylation sites