PXD005104

PXD005104 is an original dataset announced via ProteomeXchange.

Title	The CVSC mechanically reinforces HSV-1
Description	Using atomic force microscopy imaging and nanoindentation measurements, the effect of the minor capsid proteins pUL17 and pUL25 on the structural stability of the icosahedral Herpes Simplex Virus type 1 capsids was investigated. pUL17 and pUL25 that form the capsid vertex-specific component particularly contributed to the capsid resilience along the 5-fold and 2-fold, but not the 3-fold icosahedral axes. We tested whether deletion of UL17 and UL25 changed the levels of the proteins that assemble in the nucleocapsid by quantitative mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2017-04-20
AnnouncementXML	Submission_2017-04-20_00:16:40.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Eleonora Corradini
SpeciesList	scientific name: Herpes simplex virus (type 1 / strain F); NCBI TaxID: 10304;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-10-05 23:58:10	ID requested
⏵ 1	2017-04-20 00:16:41	announced

Dataset with its publication pending

curator keyword: Biological

submitter keyword: HSV-1, LC-MS/MS

Albert J.R. Heck
contact affiliation	Biomolecular mass spectrometry and proteomics, Utrecht University, Utrecht, The Netherlands
contact email	a.j.r.heck@uu.nl
lab head
Eleonora Corradini
contact affiliation	Biomolecular and mass spectrometry group
contact email	e.corradini1@uu.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/04/PXD005104

PRIDE project URI

• PRIDE
  1. PXD005104
     1. Label: PRIDE project
     2. Name: The CVSC mechanically reinforces HSV-1